Yeast - Reference Chromosome VIII


Science 265: 2077-2082 (1994) [94378003]

Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.

Johnston, M., Andrews, S., Brinkman, R., Cooper, J., Ding, H., Dover, J., Du, Z., Favello, A., Fulton, L., Gattung, S., Geisel, C., Kirsten, J., Kucaba, T., Hillier, L., Jier, M., Johnston, L., Langston, Y., Latreille, P., Louis,E.J., Macri, C., Mardis, E., Menezes, S., Mouser, L., Nhan, M., Rifk in, L., Riles, L., St.Peter, H., Trevaskis, E., Vaughan, K., Vignati, D., Wilcox, L., Wohldman, P., Waterston, R., Wilson, R., and Vaudin, M.

Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110.

The complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII reveals that it contains 269 predicted or known genes (300 base pairs or larger). Fifty-nine of these genes (22 percent) were previously identified. Of the 210 novel genes, 65 are predic ted to encode proteins that are similar to other proteins of known or predicted function. Sixteen genes appear to be relatively recently duplicated. On average, there is one gene approximately every 2 kilobases. Although the coding density and base composition across the chromosome are not uniform, no regular pattern of variation is apparent.

EMBL accession numbers: U11583, U11582, U11581, U10555, U10400, U10399, U00062, U000061, U10556, U00060, U00059, U10398, U10397, U00027, U00028, U00030, U00029