Cell cycle control of DNA replication in S.cerevisiae
Click the appropriate protein name to get information about the corresponding protein of the pathway.
This page was kindly provided by Joel A. Huberman
Cell cycle control of S phase: a comparison of two yeasts.
Chromosoma 105:197-203 (1996)
Cell cycle regulation of DNA replication in Saccharomyces cerevisiae.
The black outer circle represents the phases of the cell cycle. The inner
circle represents changes in the proteins bound to a typical replication
origin during the cell cycle. Red indicates that the origin is bound by
a "pre-replicative complex" (pre-RC), consisting of ORC plus additional
proteins (see text).
Yellow indicates the post-replicative state, when only ORC binding is
detectable. In the remainder of the diagram, each group of proteins enclosed
in a solid oval is thought to be part of a multi-protein complex. Proteins
enclosed in dashed ovals are degraded by proteolysis.
Arrowheads indicate stimulation; small solid rectangles indicate inhibition.
Thicker lines indicate processes that appear to be more important or more
fundamental for replication control within the cell cycle.
Generated Fri Nov 21 1997