Yeast - Physiological and Genetic Pathways


RNA Polymerase II Transcription Initiation Machinery

Click the appropriate protein or complex name to get information about the corresponding protein or complex.
This page was kindly provided by Richard A. Young.
F.C.P. Holstege, E.G. Jenning, J.J. Wyrick, Tong Ihn Lee, C.J. Hengartner, M.R. Green, T.R. Golub, E.S. Lander, and R.A. Young
Dissecting the Regulatory Circuitry of a Eukaryotic Genome
Cell 95: 717-728 (1998)

Model of RNA Polymerase II Transcription Initiation Machinery.The machinery depicted here encompasses over 85 polypeptides in ten (sub) complexes: core RNA polymerase II (RNAPII) consists of 12 subunits; TFIIH, 9 subunits; TFIIE, 2 subunits; TFIIF, 3 subunits; TFIIB, 1 subunit, TFIID, 14 subunits; core SRB/mediator, more than 16 subunits; Swi/Snf complex, 11 subunits; Srb10 kinase complex, 4 subunits; and SAGA, 13 subunits.
Generated Mon Jan 11 1999 Last modified: Tue Feb 10 10:33:14 CET 2004