Mechanisms for intron splicing

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  1. Splicing always involves two events :
  2. Phosphodiester bonds at the exon-intron boundaries are broken.
  3. A new phosphodiester bond is formed between the 3'-end of the upstream exon and the 5'-end of the downstream exon.

  4. Several different mechanisms exist for doing this :
  5. Nuclear pre-mRNA or spliceosomal introns.
  6. tRNA introns.
  7. Self-splicing introns : Group I and Group II introns.

  8. SpliceosomaltRNAGroup IGroup II

    Last modified: Tue Feb 10 11:20:25 CET 2004