Yeast - Putative targets of the GCN4 transcription factor

mips


This table was kindly provided by Oren Schuldiner (orensh@leonardo.ls.huji.ac.il)

See Schuldiner,O., Yanover,C. and Benvenisty,N.
Computer analysis of the entire budding yeast genome for putative targets of the GCN4 transcription factor.
Curr Genet 33:16-20 (1998)


ORF
gene
Gcn4p binding elements
closest Gcn4p BE
furthest Gcn4p BE
brief ID (from MIPS)
YAL044c
GCV3
3
67
229
glycine decarboxylase, subunit H
YAR015w
ADE1
3
52
228
phosphoribosylamidoimidazole-succinocarboxamide synthase
YBL022c
PIM1
3
171
596
ATP-dependent protease, mitochondrial
YBR139w  
3
248
498
strong similarity to carboxypeptidase
YBR218c
PYC2
3
268
598
pyruvate carboxylase 2
YBR248c
HIS7
3
135
578
glutamine amidotransferase/cyclase
YBR249c
ARO4
3
299
546
2-dehydro-3-deoxyphosphoheptonate aldolase, tyrosine-inhibited
YCL064c
CHA1
3
218
522
L-serine/L-threonine deaminase
YCL030c
HIS4
5
172
314
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase/histidinol dehydrogenase
YCL009c
ILV6
4
137
532
acetolactate synthase, regulatory subunit
YDL247w  
4
268
365
strong similarity to sugar transport proteins
YDL067c
COX9
3
255
571
cytochrome-C oxidase chain VIIA
YDL066w
IDP1
3
112
485
isocitrate dehydrogenase (NADP+), mitochondrial
YDL025c  
3
83
414
ser/thr protein kinase of the DEAD/DEAH box family
YDR354w
TRP4
3
154
249
anthranilate phosphoribosyltransferase
YER065c
ICL1
3
197
500
isocitrate lyase
YER069w
ARG5,6
3
181
358
acetylglutamate kinase and acetylglutamyl-phosphate reductase
YFL001w
DEG1
3
292
500
pseudouridine synthase
YGL234w
ADE5,7
3
188
284
phosphoribosylamine-glycine ligase and phosphoribosylformylglycinamidine cyclo-ligase
YGL184c   
3
263
379
similarity to cystathionine beta-lyase
YGL145w
TIP20
3
91
550
required for ER to Golgi transport
YGL091c
NBP35
3
137
477
nucleotide-binding protein
YGR055w
MUP1
3
112
276
high affinity methionine permease
YGR061c
ADE6
3
188
342
5'-phosphoribosylformyl glycinamidine synthetase
YGR155w
CYS4
3
286
482
cystathionine beta-synthase
YGR191w
HIP1
3
50
382
histidine permease
YGR258c
RAD2
3
269
558
structure-specific nuclease of the nucleotide excision repairosome
YHL027w
RIM101
3
156
332
meiotic regulatory protein
YHL004w
MRP4
3
43
487
ribosomal protein of the small subunit, mitochondrial
YHL003c
LAG1
3
297
507
longevity-assurance protein
YHR046c  
4
231
396
similarity to inositolmonophosphatases
YHR143w-a
RPC10
3
300
498
DNA-directed RNA polymerases I, II, III 7.7 KD subunit
YIL142w
CCT2
4
250
512
chaperonin of the TCP1 ring complex, cytosolic
YIL116w
HIS5
4
206
359
histidinol-phosphate aminotransferase
YIL085c
KTR7
3
226
583
putative alpha-1,2-mannosyltransferase
YIL078w
THS1
3
75
581
threonyl tRNA synthetase, cytosolic
YIR034c
LYS1
3
125
563
saccharopine dehydrogenase
YJL160c  
3
151
264
member of the Pir1p/Hsp150p/Pir3p family
YJL137c
GLG2
3
164
491
self-glucosylating initiator of glycogen synthesis
YJL101c
GSH1
3
87
374
glutamate--cysteine ligase
YJR066w
TOR1
3
55
339
phosphatidylinositol 3-kinase
YJR160c  
4
257
354
strong similarity to Mal3Tp
YKL218c  
3
185
553
strong similarity to threonine dehydratase
YKL060c
FBA1
3
252
490
fructose-bisphosphate aldolase II
YKL015w
PUT3
3
237
535
positive activator of the proline utilisation pathway
YKR072c
SIS2
3
258
482
involved in cell cycle-specific gene expression
YKR080w
MTD1
3
178
282
methylenetetrahydrofolate dehydrogenase (NAD+)
YLR058c
SHM2
4
220
405
serine hydroxymethyltransferase, cytoplasmic
YLR237w
THI7
3
55
568
thiamin transport protein
YLR355c
ILV5
3
127
330
ketol-acid reducto-isomerase
YML104c
MDM1
3
274
566
intermediate filament protein
YML096w    
3
150
233
similarity to asparagine synthases
YMR017w
DBI9
3
143
527
Dbf2p interacting protein
YMR064w
AEP1
3
104
477
nuclear control of ATPase messenger RNA expression protein
YMR271c
URA10
3
146
216
orotate phosphoribosyltransferase2
YMR287c
MSU1
3
220
551
3'-5' exonuclease for RNA 3' ss-tail, mitochondrial
YNL318c
HXT14
3
115
514
hexose transport protein
YNL229c
URE2
3
101
556
nitrogen catabolite repression regulator
YNL227c  
3
271
598
similarity to dnaJ-like proteins
YNL221c
POP1
3
259
488
protein component of ribonuclease P and ribonuclease MRP
YNL220w
ADE12
3
230
459
adenylosuccinate synthetase
YNL183c
NPR1
3
221
333
ser/thr protein kinase
YNL104c
LEU4
3
88
412
2-isopropylmalalate synthase
YNL103w
MET4
3
119
569
transcriptional activator of sulfur metabolism
YNL036w
NCE3
3
120
420
involved in non-classical protein export pathway
YNL005c
MRPL2
3
97
598
ribosomal protein YmL2 precursor, mitochondrial
YNL004w
HRB1
4
113
553
similarity to Gbp2p
YNR028w  
4
94
539
similarity to peptidylprolyl isomerase Scc3p
YNR056c
BIO5
3
76
275
similarity to choline transport protein CTR1
YOL095c  
5
139
518
similarity to S.aureus DNA helicase PCRA
YOL068c
HST1
3
89
462
silencing protein
YOR202w
HIS3
3
126
294
imidazoleglycerol-phosphate dehydratase
YOR206w  
3
200
359
similarity to Brettanomyces RAD4 and to S.pombe hypothetical protein
YOR226c  
3
200
517
strong similarity to nitrogen fixation proteins
YOR236w
DFR1
5
181
581
dihydrofolate reductase
YOR335c
ALA1
3
40
500
alanyl-tRNA synthetase, cytosolic
YOR351c
MEK1
3
81
295
ser/thr protein kinase
YPR001w
CIT3
3
167
467
citrate (si)-synthase, mitochondrial
YPR035w
GLN1
3
102
272
glutamate--ammonia ligase
YPR167c
MET16
3
135
517
3'-phosphoadenylylsulfate reductase
YPR178w
PRP4
4
149
417
U4/U6 snRNP 52 KD protein
 
The list includes those genes harboring 3 or more GCN4 binding elements in the region between -40 to -600 (the first ATG is 0). Only genes that have a known function in MIPS are specified. The numbers of GCN4 binding elements and the location of the first and last GCN4 binding element are shown.

Generated Mon Mar 23 1998 (zollner@mips.embnet.org)