Yeast - Impact of the gene product of MIG1 upon the expression of other genes

mips


This table was kindly provided by Christopher Klein
(ck@ibt.dtu.dk)


See Klein,C.J.L. et al.
Glucose control in S. cerevisiae: the role of MIG1 in metabolic functions
Microbiology 144:13-24 (1998)

Peripheral part of metabolism affected

 
 
Syst. name Gene name(s) Protein function of gene product EC  (Putative) Mig1- binding site Physiological effect after 

MIG1-

Disr. Overexpr.

Reference(s)
YLL043w FPS1 Osmosensitive glycerol uptake / efflux facilitator   yes yes NT LITERATURE
YBR020w GAL1 galactokinase 2.7.1.6 yes yes yes LITERATURE
YDR009w GAL3 inducer function protein   yes  NT NT LITERATURE
YPL248c GAL4 transcriptional activator   yes yes yes LITERATURE
YMR105c GAL5

(PGM2)

phosphoglucomutase 2 2.7.5.1 yes  NT NT LITERATURE
YCL040w 

YFR053c

GLK1

HXK1

glucokinase 1

hexokinase 1

2.7.1.2

2.7.1.1

yes

yes

 NT NT LITERATURE
YMR011w YDR345c YHR092c HXT2, HXT3, HXT4 (LGT1) hexose transporter, glucose sensor   yes yes NT LITERATURE
YDL194w SNF3 glucose sensor, hexose transporter     yes NT LITERATURE
YBR297w MALR regulatory protein   yes yes yes LITERATURE
YBR299w MALS maltase 3.2.1.20 yes yes yes LITERATURE
YBR298c MALT maltose transporter   yes yes yes LITERATURE
  MEL1 melibiase 3.2.1.22 yes  NT  NT LITERATURE
YIL162w SUC2 invertase 3.2.1.26 yes yes yes LITERATURE
 

 

Central part of metabolism affected

 
 
Syst. name Gene name(s) Protein function of gene product EC (Putative) Mig1 binding site Physiological effect after 

MIG1-

Disr. Overexpr.

Reference(s)
YMR280c CAT8 regulatory protein Cat8p, derepressor of FBP1, PCK1, ICL1 and ACS1   yes yes NT LITERATURE
YIL111w COX5B cytochrome c oxidase subunit Vb 1.9.3.1 yes  NT NT LITERATURE
YOR065w CYT1 cytochrome c 1   yes  NT NT LITERATURE
YLR377c FBP1 fructose-1,6-bisphosphatase 3.1.3.11 yes no no LITERATURE
YBR126c

 

GGS1,

(BYP1-3,

CIF1,

FDP1,

TPS1,

TSS1)

subunit of trehalose-6-phosphate synthase, regulator of carbon catabolite inactivation, controller of glucose flux into glycolysis 2.4.1.15 yes NT  NT LITERATURE
YKL109w HAP4 activation factor for transcription of genes involved in the oxidative phosphorylation, tricarboxylic acid cycle, and gluconeogenesis   yes no NT LITERATURE
YER065c ICL1 isocitrate lyase 4.1.3.1 yes no NT LITERATURE
YGL035c MIG1 repressor protein   yes  NT NT LITERATURE
YNL117w MLS1 malate synthase 4.1.3.2 yes  NT NT LITERATURE
YDR001c NTH1 neutral trehalase 3.2.1.28 yes  NT NT LITERATURE
YKR097w PCK1 phosphoenolpyruvate carboxykinase 4.1.1.49 yes no no LITERATURE
YLR044c PDC1 pyruvate decarboxylase (isoenzyme 1) 4.1.1.1 yes  NT NT LITERATURE
YJL166w

YGR183c

QCR8

QCR9

ubiquinol-cytochrome c oxidoreductase subunits VIII and IX 1.10.2.2 yes  NT NT LITERATURE


Last update: Wed Mar 11 1998 (zollner@mips.embnet.org)