Yeast - Examples of uORF-containing leaders in S.cerevisiae

mips


This table was kindly provided by Cristina Vilela (mjfi8cv2@fs1.ce.umist.ac.uk)

See Vilela,C. et al.
The yeast transcription factor genes YAP1 and YAP2 are subject to differential control at the levels of both translation and mRNA stability.
Nucleic Acids Research 26:1150-1159(1998)


Gene
Length of major 5'-UTR
No. and size of uORFs (codons)
Product
CBS1
101
uORF (4)
PET gene involved in the 5'end processing of the cytochrome b (LITERATURE)
CPA1
244
uORF (26)
Small subunit of cytosolic carbamoyl phosphate synthetase (LITERATURE)
DCD1
33
uORF (4)
dCMP deaminase (LITERATURE)
GCN4
591
uORF1 (4) 
uORF2 (3) 
uORF3 (4) 
uORF4 (4)
Transcriptional activator of amino acid biosynthetic pathway (LITERATURE)
HAP4
~280
uORF1 (10)
uORF2 (4)
Subunit of transcriptional activator complex binding CCAAT (LITERATURE)
HOL1
~385
uORF (6)
Major facilitator family (drug resistance subfamily) of putative transport proteins (LITERATURE)
LEU4
85
uORF1 (13)
a-isopropylmalate synthase (cytoplasmic) (LITERATURE)
PET111
459
uORF1 (6)
uORF2 (31)
uORF3 (11)
uORF4 (30)
Mitochondrial translational activator (LITERATURE)
PPR1
50
uORF (6)
Regulatory protein controlling transcription of two genes in pyrimidine biosynthesis pathway (LITERATURE)
SCH9
~600
uORF (55)
Protein kinase that positively regulates the progression of yeast through G1 phase (LITERATURE)
SCO1
~150
uORF (3)
PET gene involved in the accumulation of cytochrome c oxidase subunits I and II (LITERATURE)
TIF4631
295
uORF1 (12)
uORF2 (20)
uORF3 (16)
uORF4 (8)
uORF5 (12)
uORF6 (22)
Translation initiator factor p150 (LITERATURE)
YAP1
164
uORF (7)
Stress related transcription factor (LITERATURE)
YAP2
157
uORF1 (6)
uORF2 (23)
Stress related transcription factor (LITERATURE)
 

Generated Wed Mar 25 1998 (zollner@mips.embnet.org)